Key moments from Iowa State's win against Tennessee State in NCAA Tournament

It's the most points the Cyclones have scored in an NCAA Tournament and the largest NCAA Tournament win in program history. 

Here are some of the key moments from the game:

Iowa State's game pushed back after Kentucky overtime win

1:46 p.m. | Pregame

Iowa State's game against TSU will start around 2:02 p.m., after being initially scheduled for 1:50 p.m. No. 7 Kentucky defeated No. 10 Santa Clara in overtime 89-84.

The winner of ISU and TSU will face Kentucky on Sunday. 

Joshua Jefferson leaves game with left leg/ankle injury

17:24 1H | Iowa State leads 5-3

Unanimous ISU All-American Joshua Jefferson injured his lower left leg after making a layup. Jefferson slapped the court as trainers came out to look at his left ankle.

Medical staffers helped Jefferson off the court and took him back to ISU's locker room. He was unable to put any weight on his left leg.

Sideline reporter Jon Rothstein said Jefferson is receiving X-Rays. No update yet. 

Cyclones on 23-0 run in first half

9:26 1H | ISU leads 32-7

Since the 14:40 mark the Cyclones are on a 17-0 run. 

The run has included Three-pointers from Milan Momcilovic, Jamarion Batemon and Nate Heise. 

Joshua Jefferson "doubtful to return" to Tennessee State game

8:14 1H | ISU leads 35-9

Iowa State All-American Joshua Jefferson left the game with an apparent left ankle injury. He received x-rays in the locker room and, according to a team spokesperson is "doubtful to return."

Iowa State enters halftime with big lead

HALF | ISU leads 55-29

The Tigers have found their footing late in the second half and prevented any runs more than seven points. TSU guard Aaron Nkrumah made a contested three-pointer to send TSU into the break down 26.

Joshua Jefferson ruled out for game, sitting on Cyclone bench

15:57 2H | ISU leads 65-37

Iowa State has ruled out Jefferson for the remainder of the game. 

After halftime, Jefferson emerged from the locker room and is sitting on the last chair of the Cyclone bench. He has his left leg propped op on a stool with his foot in a boot.

End of Iowa State's blowout gets chippy

7:30 2H | ISU leads 90-55

Tennessee State's Kavien Jones was ejected after earning a flagrant two foul. ISU's Dom Pleta faked a shot and got Jones to jump. He grabbed around Pleta's neck while crashing to the court.